Process Modeller

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted, and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop, and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Opportunity

As a Process Modeller Drug Substance within Synthetic Molecules Process Development (PTDC), you will be a critical expert supporting Drug Substance (DS) project teams. Your primary focus will be leveraging chemical and process engineering principles, coupled with advanced modeling techniques, to successfully scale-up chemical processes from the laboratory to multi-purpose manufacturing equipment. You will be instrumental in defining robust scale-down conditions and ensuring essential engineering considerations are embedded in process design from the outset.

• Drive Scale-Up/Scale-Down: Provide crucial process and chemical engineering input to support the successful scale-up, scale-down, and optimization of unit operations for both batch and continuous processes.

• Embed Engineering in Design: Support early-stage process development by ensuring that key engineering and process considerations are meticulously built into the process design at the laboratory scale.

• Expand Modeling Platform: Develop and expand our internal scale-up/scale-down models self-service platform, simplifying user interfaces for generalist applications across various unit operations. Grow relationships with Universities and external research consortia to help Roche stay at the forefront of Process Modeling.

• Cross-Functional Collaboration: Work as a vital member of cross-functional teams, collaborating closely with process and plant chemists, engineering experts, and data scientists.

• Regulatory Contribution: Apply your engineering expertise and process models to contribute to regulatory filings, including supporting the definition of design spaces and justification of scale-down models.

• Technology Assessment: Actively follow and assess technological progress in the market and competitive field, identifying meaningful new technologies for implementation within our organization.

• Optimization and Insight: Utilize your modeling techniques and data-based insights to drive business results, uncover hidden solutions in experimental datasets, and improve process outcomes.

• Technical Mentorship: Act as a role model and catalyst for process modeling, utilizing your engineering and modeling expertise to proactively support and guide project teams.

Who you are:

You are an accomplished Chemical or Process Engineer with a deep understanding of reacting systems and a passion for applying advanced modeling and data science to pharmaceutical process development.

• Advanced Education and Experience: You possess a higher education (at least Master's level) in Chemical or Process Engineering or a related field, coupled with a minimum of 10 years of relevant professional experience.

• Chemical Process Expertise: Demonstrated experience in designing and scaling chemical processes, including the application of physical organic chemistry and/or kinetic modeling to chemical engineering of reacting systems.

• Modeling Tool Proficiency: Proven experience in the field of process engineering/modeling in the chemical or pharmaceutical industry, ideally with experience using tools such as gPROMS/gWAP or Dynochem. Experience in building models using Python or MATLAB or another coding language.

• Process Knowledge: Strong knowledge of chemistry, chemical processes, and equipment, including expertise in process design and optimization, especially with multiphase systems, mixing, and distillations across various scales.

• Data-Driven Approach: A strong drive to learn and master new technologies and modeling techniques, with a passion for process development and data science to improve business outcomes.

• Conceptual Agility: Possesses strong conceptual thinking skills, comfortable diving into detailed project work while also abstracting learnings into robust general workflows.

• CFD Experience (Plus): Experience with computational fluid dynamics (CFD) and relevant software such as COMSOL or M-Star is considered a plus.

• Collaboration and Communication: Excellent teamwork and communication skills are essential for collaborating closely with the business; excellent command of written and spoken English is required (German is a plus). 

Ready to bring your unique qualities to Roche and make an impact? Apply now and join us in our mission to shape the future of healthcare.

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.